The bioinformatics and computational biology software and databases offered through this page were created by researchers at the National Institute of Allergy and Infectious Diseases (NIAID) which is part of the US National Institutes of Health (NIH).


The Desktop cDNA Annotation System (dCAS) automates large-scale cDNA sequence analysis by allowing a researcher to import raw cDNA sequences, clean sequences, perform SignalP analysis, BLAST contigs against numerous BLAST databases, and view the results in a Microsoft Excel worksheet.


SPICE is a data mining software application that analyzes large FLOWJO data sets from polychromatic flow cytometry and organizes the normalized data graphically. SPICE enables users to discover potential correlations in their experimental data within complex data sets.


The DAPfinder plug-in for BRB-ArrayTools uses a Fisher's Z test to compare gene-gene Pearson, Spearman or Kendall correlations between two classes and it provides an option to compare gene-gene mutual information, Pearson, Spearman or Kendall correlations between two classes with a permutation test.


Software for the 3D reconstruction via stereoscopy for the study of mosquito swarms


The Networks on Circular Chromosome (NetCirChro) tool has been developed by the NIAID Bioinformatics and Computational Bioscience Branch (BCBB) to enable users of the network visualization platform Cytoscape to overlay networks onto a circular chromosomal map.

Transcriptome Resources

Transcriptomes of vector arthropods and non-vector, medically important arthropods and snakes


Simple graphical interface to easily define the interactions between individual molecules in a large network, or the behaviors of cells in response to external signals. It consists of three components: Modeler, Cell Designer and Simulator.

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